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The top selected feature during each quarter will receive a $5,000 cash prize
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After garnering community and internal staff approval, Browster will integrate the crème de la crème of submitted feature ideas into future updates, which will be released on a monthly basis through 2006
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, announced the closing of $2,470,000 million in financing for the Villa de Casa Apartments, a 27-unit multifamily property in Monterey, CAHoward Levine, president/CEO of ARCS Commercial Mortgage Co
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Phenylalanine side chain behavior of the intestinal fatty acid-binding protein: the effect of urea on backbone and side chain stability
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The presence of Mg^sup 2+^ slightly increased the T^sub m^ of EI^sup sc^ alone, probably due to formation of an octahedral-coordination-geometry complex to the native state of EI^sup sc^, as occurs in other homologous proteins (56,57)
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11 The pure colophony of R-type flux exhibits a weak cleaning action due to its one -COOH group in its large molecule
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The PLC-γ1 C-terminal SH2 domain (19) and Csk SH3 domain (47) bind specifically to their flexible (peptide) target to form a specific complex, again with essentially one overall conformation
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Probing substructure by chemical reactivity and spin and fluorescence labeling of engineered cysteine residues
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To quantitate the unfolding kinetics of apoA-2 on DMPC, we monitored the time course of the protein unfolding
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1 C) is invariant in repetitive CD and DSC scans (curves 2-4, Fig
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2] of sea surface) were found in December 1986, 1996, and 1999
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Hawaii Press, Honolulu, HI
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For the all-atom analysis of CD4 (Fig
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Using the Boehlert and Yoklavich (1984) equation; (stage duration = O
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Our identifying assumption in this and all other regressions is that the pre-RP trends in the outcome variable would have continued into the post-RP period had RP not been implemented
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1671#First line restrictedDiclofenac 1
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"We used to call it a trade show, and it was a lot about deals
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Pharmacy gears up for Medicaid budget battleJames FrederickALEXANDRIA, Va
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Of the 300 to 500 players in a tournament, 150 are pros like Williams (Paul Darden and Phil Ivey are two other African American stars)
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This intricate card game, combining elements of chess, poker, and Tolkien, was invented in the early 1990s for the Dungeons-and-Dragons crowd by a grad student in mathematics named Richard Garfield
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The addiction angle is the opposition's club of choice, perhaps because it sounds better to modern ears than denouncing gambling as a sin
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349,210: number of workers employed in commercial casinos in 2004$12
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. We hypothesize that this compensatory effect could be due to a change in the coordination sphere of the Mg^sup 2+^ by directly involving the phosphoryl group of the PEP moiety, as it occurs in a member of the pyruvate dikinase family (57)
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. The preceding study (12) has demonstrated that the creation of hydrophobic ANS binding sites in ice, accounting for the spectral blue shift and intensity enhancement, is owed to partial disruption of the protein tertiary structure triggered by the solidification of water
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. A rough estimate of the minimum number of binding sites, as done above with azurin, yields n ~20, which is four times larger than the corresponding value in liquid solution (5)
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. Above that temperature, the MSDs for HuBChE-D^sub 2^O are larger than those for Soman/HuBChE-D^sub 2^O, which remain in a quasiharmonic regime, as shown by their linear dependence on temperature (Fig
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. Thus, the data are consistent with a motional model in which the two N-terminal and two C-terminal CaM domains in the dimeric CaM:SEF2-lmp complex undergo a small-scale wobbling motion with a half-angle of ~20° as estimated from S^sup 2^^sub s^ = 0
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. One possibility was deactivated Gα-subunits that could displace Gβγ from PLCβ^sub 2^, but the addition of a large molar excess of Gα^sub i^(GDP)-subunits did not affect either the on- or off-rates
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. The Θ^sub 222^(t) data show slow unfolding on a timescale of 10^sup 2^-10^sup 3^ s (as compared to 10^sup -8^-10^sup -10^ s for the helix-to-coil transition in solution; Yang and Gruebele, 2003), implicating high free-energy barrier ΔG*
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.When the flat, diffusional degrees of freedom are projected away onto a reaction coordinate pair, such as R^sub g^ and [straight phi]^sub native^, then a folding funnel appears, and does so without the presence of any long-range forces
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. Very recently, the role of nonnative interactions in stabilizing an on-pathway intermediate, together with a diffusion-collision kinetic route, has been experimentally verified in the case of the immunity protein Im7 (Capaldi et al
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