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ANS binding studies ANS (1-anilino-8-naphthalene sulfonate) binding experiments were executed with both the native and recombinant protein
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This erroneous model is of interest only because it has been used previously for denatured proteins in studies aimed at correlating m values and ΔC^sub P^ to changes in solventaccessible surface area (90)
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Implications for denatured-state ensembles in strongly denaturing environments Our results have direct bearing on the development of accurate reference-state descriptions for highly denatured proteins
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This central point of regulation suggests an exploitable therapeutic target through which efferocytosis could be enhanced by the selective activation of Rat-1 or the inhibition of RhoA/Rho kinase (more below)
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ACKNOWLEDGMENT: The authors thank Dr
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Different intracelluar regions, however, cannot be distinguished this way
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The standard buffer was 10 mM Na phosphate, 0
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It shares with the present treatment the essential departure from a one-dimensional projection of a transition state, and an identification of the number of permissible pathways, or transition entropy, in controlling the rate of folding
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LarvaeIchthyoplankton was sampled by using Bongo, Nackthai, and PairoVET nets
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Using the hairpin ribozyme as a model system, we specifically address a key question in RNA folding-how do preformed secondary structure elements dictate the course of subsequent tertiary folding events? Currently, little is known about how secondary structural elements affect the ribozyme conformational distributions important in the course of folding
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t] x t [[beta]
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