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The implication is that EV-limit ensembles for proteins are likely to be close facsimiles of conformational ensembles in high concentrations of chemical denaturants
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That this is indeed the case is shown by comparing cavity statistics in the EV limit to values obtained for freely rotating chains
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(16) This exposure of PS by apoptotic cells is of particular interest, because it induces membrane ruffling and efferocytosis, and it has been implicated in many of the immunomodulatory effects associated with efferocytosis (more below)
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Protein solutions (protein concentrations: 7 µg/ml to 1 mg/ml) were tilled into quartz-cuvettes with an optical pathlength of 1 cm (104F-QS, Hellma, Muehlheim, Germany)
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To see how this works, we suppose at first that the d ~ O(10^sup 2^) dimensions of the full folding space are now arranged sequentially so that diffusive searches in one dimension at a time allow the protein to find "gateways" into the next subspace (we will see how this may arise naturally in a physical way below)
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48), and the anus was situated near the midpoint of the body (Fig
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Larvae of temperate Australian fishes
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24 kJ K^sup -1^ mol^sup -1^ (Fig
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Hence, a quasi-docked conformation could be visited many times during the course of hairpin ribozyme folding, thereby increasing the probability of forming the key tertiary contacts required for stable docking of loops A and B
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ACKNOWLEDGMENTSSupport for this project from the Health Transitions Fund, Health Canada; the Canadian Health Services Research Foundation; Brogan Inc
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Changes to this second edition include chapter examples, summaries, key terms, and boxed readings, along with expanded material on topics such as statistical theory, screening and transforming data, and ANOVA
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These findings are in keeping with changes in the totals sat on and the failure to hit errors, which indicated that participants started using the strategy in the first three or four blocks and then stopped
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